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KMID : 1123920040180030914
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Korean Journal of Oriental Physiology and Pathology
2004 Volume.18 No. 3 p.914 ~ p.918
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Antifungal Activity of Bioactive Fractions on the Dermatophytic Fungus
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Kim Myung-Ju
Na Young-Soon
Chai Kyu-Yun
Oh Hyun-Ju
Baek Seung-Hwa
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Abstract
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Cytotoxic and antifungal activities were strongly shown by Fr. 4 (218 mg, P388 IC/sub 50/ 652 ng/ml at 75 μg/disc, IC50 834 ng/ml at 30 μg/disc and HM 8). The subfraction 4 - 3 that showed the most activity was cytotoxic to murine leukaemia cells ATCC CCl 46 P388D1, (44.0 mg, P388 IC50 302 ng/ml at 30 μg/disc).
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KEYWORD
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Cytotoxic and antifungal activities, Trichophyton mentagrophytes, murine leukaemia cells
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